Opioid Conversion Calculator

Use our free Opioid Conversion calculator to quickly estimate your equivalent opioid dose (daily MME or target opioid dosing), based on key inputs like current opioid, strength per unit, units per day, route, and target opioid. Perfect for clinicians, pharmacists, and advanced practice providers. This tool converts an opioid regimen into morphine milligram equivalents (MME) and then converts MMEs into an estimated equivalent dose of a different opioid using accepted MME conversion factors. It handles single or multiple concurrent opioids, supports oral and transdermal routes where conversion factors exist, and highlights high-risk total MME values so you can flag cases that need closer review. The calculator does not replace clinical judgment — always account for cross-tolerance, patient-specific factors (age, organ function, opioid tolerance), and local formularies or PDMP guidance when making prescription changes. This tool converts an opioid regimen into morphine milligram equivalents (MME) and then converts MMEs into an estimated equivalent dose of a different opioid using accepted MME conversion factors. It handles single or multiple concurrent opioids, supports oral and transdermal routes where conversion factors exist, and highlights high-risk total MME values so you can flag cases that need closer review. The calculator does not replace clinical judgment — always account for cross-tolerance, patient-specific factors (age, organ function, opioid tolerance), and local formularies or PDMP guidance when making prescription changes.

Opioid Conversion Formula

MME = Opioid Dose × Conversion Factor
Example:
If a patient takes 30 mg of Oxycodone daily: MME = 30 × 1.5 = 45 MME/day

Understanding and using the conversion formula matters because it translates heterogeneous opioid prescriptions into a single, comparable metric (MME) so clinicians can: detect high total opioid exposure, compare and reconcile multiple prescriber regimens, and estimate equivalent dosing when switching therapies. Conversions reveal key drivers of risk (potency, route, formulation, and cumulative prescriptions) and help avoid unintentional overdosing during transitions. Edge cases—like methadone, buprenorphine, and fentanyl patches—use non-linear or product-specific factors and often require specialist input; conversion tables are meant as a guide, not a substitute for clinical judgment. Finally, always consider cross-tolerance (reduce calculated target dose), patient age, renal/hepatic function, and recent dose escalations; these factors materially change safe starting doses and monitoring needs.

How this opioid conversion calculator works

This calculator estimates your equivalent opioid dose by converting each opioid in a regimen to morphine milligram equivalents (MME) using published conversion factors, summing MMEs, and converting that total to a target opioid dose using the target’s conversion factor; optional cross-tolerance reduction is applied for safety. It’s designed to provide a fast, reproducible starting estimate so prescribers can make informed dose-change decisions.

Walkthrough & assumptions:

Input: drug name (or select), strength per unit, units per dose, doses per day, route (oral, transdermal when supported). The calculator multiplies these to get mg/day.
Conversion factors: uses standardized MME factors from clinical guidance (note: some factors have been updated; the app flags opioids with special rules like methadone, buprenorphine, and fentanyl).
Multiple opioids: converts each concurrently prescribed opioid to MME, then sums them for total daily MME.
Target dose: divides total MME by the target opioid’s MME factor to yield a theoretical equivalent total daily dose.
Safety adjustment: offers an automatic “cross-tolerance reduction” (default ~25%) to reduce the calculated target dose as a conservative starting point.
Rounding & dosing increments: suggests practical pill/patch sizes and common dosing intervals (q8h, q12h, etc.), and highlights if rounding increases risk.
Alerts: flags total MME thresholds commonly used for heightened monitoring (examples shown and customizable), and recommends naloxone co-prescribing where indicated.
Limitations: the calculator does not account for individual pharmacokinetic differences, drug interactions (e.g., CYP interactions), or acute tolerance changes — use as an adjunct to clinical evaluation and local policy.
Documentation: outputs a printable conversion summary (inputs, raw MME math, adjusted target dose, and safety notes) for charting and PDMP reconciliation.

When to use this opioid conversion calculator

Use this calculator when you need a quick, transparent estimate of equivalent opioid dosing to support safe prescribing, transitions of care, or chart reconciliation. It’s most useful at handoffs, during formulary switches, and when consolidating multi-prescriber regimens.

Converting between oral opioids during an inpatient→outpatient transfer — get a starting dose estimate and safety adjustment for cross-tolerance.

Reconciling prescriptions from multiple clinicians — sum MMEs to detect elevated cumulative exposure.

Switching from short-acting to long-acting formulations — calculate total daily MME then divide across long-acting dosing intervals.

When considering naloxone co-prescription — identify patients whose total MME or risk factors warrant naloxone.

Triage for specialist consultation — flag methadone, buprenorphine, or fentanyl patch conversions that need addiction/pain specialty input.

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ServiceAgent ROI Calculator

Average Profit Margins by Industry

Understand how healthcare-related services compare across industries. Below are typical profit margin ranges:

Hospitals & Healthcare Providers

8–15%
net margin

Pharmacies

3–5%
net margin

Pharmaceutical Companies

15–25%
net margin

Medical Device Manufacturers

20–30%
net margin

Insurance Providers

10–20%
net margin

Construction/Contracting

15–30%
net margin

Cleaning Services

50–70%
net margin

These benchmarks highlight how opioid prescribing and monitoring fit into broader healthcare economics.

Frequently Asked Questions

An opioid conversion calculator is a medical tool that estimates the equivalent dose of one opioid based on another’s strength and dosage. It converts various opioid medications into a standardized value—called morphine milligram equivalents (MME)—so clinicians can compare potency and safely switch between drugs.

MME stands for Morphine Milligram Equivalent. It standardizes opioid strength for safety and risk assessment.

No—this is an educational tool. Always consult prescribing guidelines and patient-specific factors.

It covers the most commonly prescribed opioids. For less common medications, consult clinical references.

The CDC notes increased risk of overdose at ≥50 MME/day and significant risk above 90 MME/day.

Yes—calculate baseline MME, then gradually adjust per tapering protocol.

No—dose adjustments for tolerance must be made clinically.

Pair it with ServiceAgent.ai to simplify dosage tracking, compliance, and patient safety reporting.